NACHT Domain, Leucine-Rich-Repeat, and PYD-Containing Protein 2 (NALP2) (C-Term) antibody

Details for Product No. ABIN237837
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Antigen
Epitope
C-Term
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Western Blotting (WB)
Pubmed 4 references available
Quantity 100 μg
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Immunogen Synthetic peptide corresponding to 12 AA near the carboxy terminus of human NALP2 (Genbank accession No. NP_060322).
Specificity Reacts with human, mouse and rat NALP2.
Characteristics Rabbit anti NALP2, Rabbit antibody to Human NACHT domain, Leucine-rich-repeat, and PYD-containing protein 2 (NALP2)
Purification Immuno Affinity Chromatography
Application Notes Suitable for use in Western blot (1 - 2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8 °C.
Expiry Date 12 months
General Martinon, Tschopp: "NLRs join TLRs as innate sensors of pathogens." in: Trends in immunology, Vol. 26, Issue 8, pp. 447-54, 2005 (PubMed).

Bruey, Bruey-Sedano, Newman et al.: "PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 51897-907, 2004 (PubMed).

Agostini, Martinon, Burns et al.: "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder." in: Immunity, Vol. 20, Issue 3, pp. 319-25, 2004 (PubMed).

Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).

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Catalog No. ABIN237837
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