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Details for Product No. ABIN237837

NACHT Domain, Leucine-Rich-Repeat, and PYD-Containing Protein 2 (NALP2) (C-Term) antibody

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Antigen
Epitope
C-Term
Reactivity
Human
Host
Rabbit
Clonality Polyclonal
Application
Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN237837
Quantity 100 µg
Price
451.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 4 to 5 Business Days
Immunogen Synthetic peptide corresponding to 12 AA near the carboxy terminus of human NALP2 (Genbank accession No. NP_060322).
Specificity Reacts with human, mouse and rat NALP2.
Characteristics Rabbit anti NALP2, Rabbit antibody to Human NACHT domain, Leucine-rich-repeat, and PYD-containing protein 2 (NALP2)
Purification Immuno Affinity Chromatography

Application Details

Handling References back to top
Application Notes Suitable for use in Western blot (1 - 2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8°C.
Expiry Date 12 months
Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).

Agostini, Martinon, Burns et al.: "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder." in: Immunity, Vol. 20, Issue 3, pp. 319-25, 2004 (PubMed).

Bruey, Bruey-Sedano, Newman et al.: "PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 51897-907, 2004 (PubMed).

Martinon, Tschopp: "NLRs join TLRs as innate sensors of pathogens." in: Trends in immunology, Vol. 26, Issue 8, pp. 447-54, 2005 (PubMed).

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