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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
NACHT domain, Leucine-rich-repeat, and PYD-containing protein 2 (NALP2) antibody
Western Blotting (WB)
|4 references available|
|Quantity||100ug (Lot specific)|
|Price||437.80 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 4 to 5 Business Days|
|Immunogen||Synthetic peptide corresponding to 12 amino acids near the carboxy terminus of human NALP2 (Genbank accession No. NP_060322).|
|Description||Rabbit anti NALP2 Rabbit Antibody to Human NACHT domain, Leucine-rich-repeat, and PYD-containing protein 2 (NALP2)|
|Specificity||Reacts with human, mouse and rat NALP2.|
|Application Notes||Suitable for use in Western blot (1 ? 2ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.|
|Buffer||PBS. Preservative: 0.02% Sodium Azide|
|Storage||Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.|
|Restrictions||For Research Use only|
Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).
Agostini, Martinon, Burns et al.: "NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder." in: Immunity, Vol. 20, Issue 3, pp. 319-25, 2004 (PubMed).
Bruey, Bruey-Sedano, Newman et al.: "PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 51897-907, 2004 (PubMed).
Martinon, Tschopp: "NLRs join TLRs as innate sensors of pathogens." in: Trends in immunology, Vol. 26, Issue 8, pp. 447-54, 2005 (PubMed).