RAPTOR (C-Term) antibody

Details for Product No. ABIN238046
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Antigen
Epitope
C-Term
(12), (9), (9), (6), (4), (3), (2), (1), (1)
Reactivity
Mouse (Murine)
(64), (50), (26), (25), (24), (24), (12), (12)
Host
Rabbit
(70), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(49), (24), (23), (20), (9), (9), (4), (3), (2), (1)
Pubmed 5 references available
Quantity 100 µg
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Catalog No. ABIN238046
481.80 $
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Immunogen 16 amino acid peptide from near the carboxy-terminus of mouse Raptor (Genbank accession No. Q8K4Q0)
Specificity Reacts with Mouse Raptor, C-terminal (Regulatory associated protein of TOR). Raptor has multiple isoforms that may be recognized.
Characteristics Rabbit anti Mouse Raptor (CT), Rabbit antibody to Mouse Raptor C-terminal
Purification DEAE Chromatography
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Application Notes Suitable for use in Western blot (2- g/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store at 2-8°C.
General Hara, Yonezawa, Weng et al.: "Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism." in: The Journal of biological chemistry, Vol. 273, Issue 23, pp. 14484-94, 1998 (PubMed).

Nojima, Tokunaga, Eguchi et al.: "The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 15461-4, 2003 (PubMed).

Shamji, Nghiem, Schreiber: "Integration of growth factor and nutrient signaling: implications for cancer biology." in: Molecular cell, Vol. 12, Issue 2, pp. 271-80, 2003 (PubMed).

Yonezawa, Tokunaga, Oshiro et al.: "Raptor, a binding partner of target of rapamycin." in: Biochemical and biophysical research communications, Vol. 313, Issue 2, pp. 437-41, 2003 (PubMed).

Fingar, Blenis: "Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression." in: Oncogene, Vol. 23, Issue 18, pp. 3151-71, 2004 (PubMed).

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