RAPTOR (Middle Region) antibody

Details for Product No. ABIN238047
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Middle Region
(17), (15), (12), (10), (9), (6), (3), (2), (1), (1)
(95), (52), (25), (1)
(108), (2)
(7), (7), (7), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2)
Western Blotting (WB)
(74), (27), (20), (16), (11), (10), (10), (8), (6), (6), (5), (4), (2)
Pubmed 5 references available
Quantity 100 μg
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Immunogen 15 amino acid peptide from the central region of human Raptor (Genbank accession No. Q8N122)
Specificity Reacts with Human and mouse Raptor (Regulatory associated protein of TOR). Raptor has multiple isoforms that may be recognized.
Characteristics Rabbit anti Raptor (Middle), Rabbit antibody to Raptor (Middle)
Purification Immuno Affinity Chromatography
Research Area Chromatin and Nuclear Signaling, Cell Cycle
Application Notes Suitable for use in Western blot (2- g/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2-8 °C.
General Fingar, Blenis: "Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression." in: Oncogene, Vol. 23, Issue 18, pp. 3151-71, 2004 (PubMed).

Yonezawa, Tokunaga, Oshiro et al.: "Raptor, a binding partner of target of rapamycin." in: Biochemical and biophysical research communications, Vol. 313, Issue 2, pp. 437-41, 2003 (PubMed).

Shamji, Nghiem, Schreiber: "Integration of growth factor and nutrient signaling: implications for cancer biology." in: Molecular cell, Vol. 12, Issue 2, pp. 271-80, 2003 (PubMed).

Nojima, Tokunaga, Eguchi et al.: "The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 15461-4, 2003 (PubMed).

Hara, Yonezawa, Weng et al.: "Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism." in: The Journal of biological chemistry, Vol. 273, Issue 23, pp. 14484-94, 1998 (PubMed).

Catalog No. ABIN238047
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