Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) (Middle Region) antibody

Antigen: Regulatory Associated Protein of MTOR, Complex 1 (RPTOR)

Synonyms: Raptor, dRaptor, raptor/CG4320, DmelCG4320, CG4320, KOG1, Mip1, KIAA1303, mKIAA1303, 4932417H02Rik, RP24-225K18.1, RGD1311784, RPTOR, raptor

Binding Site: Middle Region

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Catalog no.: ABIN238047

Additional Information

Alternative name: Raptor

Immunogen: 15 amino acid peptide from the central region of human Raptor (Genbank accession No. Q8N122)

Format: Liquid

Description: Rabbit anti Raptor (Middle) Rabbit Antibody to Raptor (Middle)

Specificity: Reacts with Human and mouse Raptor (Regulatory associated protein of TOR). Raptor has multiple isoforms that may be recognized.

Application Details

Application Notes: Suitable for use in Western blot (2?g/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Hara, Yonezawa, Weng et al.: "Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism." in: The Journal of biological chemistry, Vol. 273, Issue 23, pp. 14484-94, 1998 (PubMed).

Nojima, Tokunaga, Eguchi et al.: "The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 15461-4, 2003 (PubMed).

Shamji, Nghiem, Schreiber: "Integration of growth factor and nutrient signaling: implications for cancer biology." in: Molecular cell, Vol. 12, Issue 2, pp. 271-80, 2003 (PubMed).

Yonezawa, Tokunaga, Oshiro et al.: "Raptor, a binding partner of target of rapamycin." in: Biochemical and biophysical research communications, Vol. 313, Issue 2, pp. 437-41, 2003 (PubMed).

Fingar, Blenis: "Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression." in: Oncogene, Vol. 23, Issue 18, pp. 3151-71, 2004 (PubMed).