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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Regulatory Associated Protein of MTOR, Complex 1 (RPTOR) (N-Term) antibody
|Synonyms||Raptor, dRaptor, raptor/CG4320, DmelCG4320, CG4320, KOG1, Mip1, KIAA1303, mKIAA1303, 4932417H02Rik, RP24-225K18.1, RGD1311784, RPTOR, raptor|
Alternatives Western Blotting (WB)
|5 references available|
|Quantity||100ug (Lot specific)|
|Price||468.60 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 4 to 5 Business Days|
|Immunogen||13 amino acid peptide from near the amino-terminus of human Raptor (Genbank accession No. Q8N122)|
|Description||Rabbit anti Raptor (NT) Rabbit Antibody to Raptor (NT)|
|Specificity||Reacts with Human and mouse Raptor, N-terminal (Regulatory associated protein of TOR). Raptor has multiple isoforms that may be recognized.|
|Application Notes||Suitable for use in Western blot (2?g/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.|
|Buffer||PBS. Preservative: 0.02% Sodium Azide|
|Storage||Store at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.|
|Restrictions||For Research Use only|
Hara, Yonezawa, Weng et al.: "Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism." in: The Journal of biological chemistry, Vol. 273, Issue 23, pp. 14484-94, 1998 (PubMed).
Nojima, Tokunaga, Eguchi et al.: "The mammalian target of rapamycin (mTOR) partner, raptor, binds the mTOR substrates p70 S6 kinase and 4E-BP1 through their TOR signaling (TOS) motif." in: The Journal of biological chemistry, Vol. 278, Issue 18, pp. 15461-4, 2003 (PubMed).
Shamji, Nghiem, Schreiber: "Integration of growth factor and nutrient signaling: implications for cancer biology." in: Molecular cell, Vol. 12, Issue 2, pp. 271-80, 2003 (PubMed).
Yonezawa, Tokunaga, Oshiro et al.: "Raptor, a binding partner of target of rapamycin." in: Biochemical and biophysical research communications, Vol. 313, Issue 2, pp. 437-41, 2003 (PubMed).
Fingar, Blenis: "Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression." in: Oncogene, Vol. 23, Issue 18, pp. 3151-71, 2004 (PubMed).