Human RING Finger Protein 4 (BMI-1) antibody

Antigen: Human RING Finger Protein 4 (BMI-1)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN238069

Additional Information

Immunogen: Synthetic peptide corresponding to 15 amino acids near the center of human BMI-1 (Genbank accession No. P35226).

Format: Affinity-purified, Liquid

Description: Rabbit anti BMI-1 Rabbit Antibody to Human RING finger protein 4 (BMI-1)

Specificity: Reacts with human, mouse and rat BMI-1.

Application Details

Application Notes: Suitable for use in Western blot (0.5 ? 1ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Publications: Alkema, Wiegant, Raap et al.: "Characterization and chromosomal localization of the human proto-oncogene BMI-1." in: Human molecular genetics, Vol. 2, Issue 10, pp. 1597-603, 1994 (PubMed).

Jacobs, Kieboom, Marino et al.: "The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus." in: Nature, Vol. 397, Issue 6715, pp. 164-8, 1999 (PubMed).

Lessard, Sauvageau: "Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells." in: Nature, Vol. 423, Issue 6937, pp. 255-60, 2003 (PubMed).