SARS (Severe Acute Respiratory Syndrome) Spike Protein (Middle Region) antibody

Antigen: SARS (Severe Acute Respiratory Syndrome) Spike Protein

Binding Site: Middle Region

Clonality: Polyclonal

Host: Rabbit

Application: ELISA

Catalog no.: ABIN238100

Additional Information

Immunogen: Synthetic peptide corresponding to amino acids near the center of the SARS Spike glycoprotein (Genbank accession no. P59594).

Format: Liquid

Description: Rabbit A’ SARS Spike (Middle) Rabbit Antibody to SARS (Severe Acute Respiratory Syndrome) Spike protein, Middle region

Specificity: Reacts with amino acids near the middle of the spike protein of SARS-associated coronavirus. The spike protein is a glycosylated 139 kDa protein and the major surface antigen of the virus.

Application Details

Application Notes: Suitable for use in ELISA. It will detect 10ng of free peptide at 1ug/ml. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Rota, Oberste, Monroe et al.: "Characterization of a novel coronavirus associated with severe acute respiratory syndrome." in: Science (New York, N.Y.), Vol. 300, Issue 5624, pp. 1394-9, 2003 (PubMed).

Marra, Jones, Astell et al.: "The Genome sequence of the SARS-associated coronavirus." in: Science (New York, N.Y.), Vol. 300, Issue 5624, pp. 1399-404, 2003 (PubMed).

Li, Moore, Vasilieva et al.: "Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus." in: Nature, Vol. 426, Issue 6965, pp. 450-4, 2003 (PubMed).

Navas-Martín, Weiss: "Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development." in: Journal of neurovirology, Vol. 10, Issue 2, pp. 75-85, 2004 (PubMed).