TNF Receptor-Associated Factor 3 (TRAF3) (C-Term) antibody

Antigen: TNF Receptor-Associated Factor 3 (TRAF3)

Synonyms: LAP1, CAP-1, CRAF1, CD40bp, amn, T-BAM, AI528849, LOC100218184

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN238216

Additional Information

Immunogen: Synthetic peptide corresponding to 16 amino acids near the carboxy terminus of Human TRAF3 (Genbank accession No. NP_663777)

Format: Liquid

Description: Rabbit anti TRAF3, C-term. Rabbit Antibody to Human TNF Receptor-Associated Factor 3 (TRAF3), C-terminal

Specificity: Reacts with human and mouse TRAF3.

Application Details

Application Notes: Suitable for use in Western blot (1 ? 2ug/ml) and immunohistochemistry (2ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Cheng, Cleary, Ye et al.: "Involvement of CRAF1, a relative of TRAF, in CD40 signaling." in: Science (New York, N.Y.), Vol. 267, Issue 5203, pp. 1494-8, 1995 (PubMed).

Mosialos, Birkenbach, Yalamanchili et al.: "The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family." in: Cell, Vol. 80, Issue 3, pp. 389-99, 1995 (PubMed).

Arch, Gedrich, Thompson: "Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death." in: Genes & development, Vol. 12, Issue 18, pp. 2821-30, 1998 (PubMed).

Kuai, Nickbarg, Wooters et al.: "Endogenous association of TRAF2, TRAF3, cIAP1, and Smac with lymphotoxin beta receptor reveals a novel mechanism of apoptosis." in: The Journal of biological chemistry, Vol. 278, Issue 16, pp. 14363-9, 2003 (PubMed).