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|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) antibody
|Synonyms||APO3L, DR3LG, TWEAK, MGC20669, MGC129581|
Alternatives Western Blotting (WB)
|5 references available|
|Quantity||100ug (Lot specific) (Variants)|
|Price||465.67 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 4 to 5 Business Days|
|Alternative name||TNF-related Weak inducer of Apoptosis (TWEAK)|
|Immunogen||Recombinant Human TWEAK (Genbank accession No. NP_003800)|
|Description||Rabbit anti TWEAK Rabbit Antibody to Human TNF-related Weak inducer of Apoptosis (TWEAK)|
|Specificity||Reacts with human, mouse and rat TWEAK.|
|Application Notes||Suitable for use in Western blot (0.5 ? 1ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.|
|Buffer||PBS. Preservative: 0.02% Sodium azide|
|Storage||Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.|
|Restrictions||For Research Use only|
Chicheportiche, Bourdon, Xu et al.: "TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32401-10, 1998 (PubMed).
Lynch, Wang, Lund et al.: "TWEAK induces angiogenesis and proliferation of endothelial cells." in: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8455-9, 1999 (PubMed).
Chicheportiche, Chicheportiche, Sizing et al.: "Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies." in: Arthritis research, Vol. 4, Issue 2, pp. 126-33, 2002 (PubMed).
Kaplan, Lewis, Shelden et al.: "The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 6020-9, 2002 (PubMed).
Wiley, Winkles: "TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor." in: Cytokine & growth factor reviews, Vol. 14, Issue 3-4, pp. 241-9, 2003 (PubMed).
|Hosts||Rabbit (28), Goat (10), Rat (8), Mouse (5)|
|Reactivities||Human (39), Mouse (Murine) (17), Rat (Rattus) (6), Dog (Canine) (2)|
|Applications||Western Blotting (WB) (38), ELISA (24), Flow Cytometry (FACS) (15), Immunohistochemistry (IHC) (7), Immunofluorescence (IF) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (3), Functional Studies (Func) (2), Neutralization (Neut) (2), Blocking Antibody (Inhibition) (1), Blocking Antibody (Inhibition) (1), Immunocytochemistry (ICC) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)|
|Conjugates||Biotin (8), PE (3)|
|Epitopes||N-Term (2), AA 106-249 (1), Internal Region (1)|