Tumor Necrosis Factor (Ligand) Superfamily, Member 12 (TNFSF12) antibody

Details for Product No. ABIN238217
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Antigen
Synonyms APO3L, DR3LG, TWEAK, Apo3l, Dr3l, Dr3lg, Tweak
Reactivity
Human
(61), (36), (11), (2)
Host
Rabbit
(42), (16), (13), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(10), (6)
Application
Western Blotting (WB)
(53), (31), (25), (17), (9), (8), (7), (4), (4), (2), (2), (2)
Pubmed 5 references available
Quantity 100 µg
Options
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Catalog No. ABIN238217
478.87 $
Plus shipping costs $45.00

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Immunogen Recombinant Human TWEAK (Genbank accession No. NP_003800)
Specificity Reacts with human, mouse and rat TWEAK.
Characteristics Rabbit anti TWEAK, Rabbit antibody to Human TNF-related Weak inducer of Apoptosis (TWEAK)
Purification Immuno Affinity Chromatography
Alternative Name TNF-related Weak inducer of Apoptosis (TWEAK)
Application Notes Suitable for use in Western blot (0.5 - 1 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8°C.
Expiry Date 12 months
General Chicheportiche, Bourdon, Xu et al.: "TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis." in: The Journal of biological chemistry, Vol. 272, Issue 51, pp. 32401-10, 1998 (PubMed).

Lynch, Wang, Lund et al.: "TWEAK induces angiogenesis and proliferation of endothelial cells." in: The Journal of biological chemistry, Vol. 274, Issue 13, pp. 8455-9, 1999 (PubMed).

Chicheportiche, Chicheportiche, Sizing et al.: "Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies." in: Arthritis research, Vol. 4, Issue 2, pp. 126-33, 2002 (PubMed).

Kaplan, Lewis, Shelden et al.: "The apoptotic ligands TRAIL, TWEAK, and Fas ligand mediate monocyte death induced by autologous lupus T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 10, pp. 6020-9, 2002 (PubMed).

Wiley, Winkles: "TWEAK, a member of the TNF superfamily, is a multifunctional cytokine that binds the TweakR/Fn14 receptor." in: Cytokine & growth factor reviews, Vol. 14, Issue 3-4, pp. 241-9, 2003 (PubMed).

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