Toll-Like Receptor 5 (TLR5) (C-Term) antibody

Antigen: Toll-Like Receptor 5 (TLR5)

Synonyms: TIL3, SLEB1, FLJ10052, MGC126430, MGC126431, TLR5, TLR-5, tlr-5

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN238222

Additional Information

Immunogen: Synthetic peptide corresponding to 15 amino acids near the carboxy terminus of Human TLR5 (Genbank accession No. NP_003259).

Format: Liquid

Description: Rabbit anti TLR5, C-term. Rabbit Antibody to Human Toll-like Receptor 5 (TLR5), C-terminal

Specificity: Reacts with human and mouse TLR5.

Application Details

Application Notes: Suitable for use in Western blot (1 ? 2ug/ml) and Immunohistochemistry (10ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity chromatography

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Hayashi, Smith, Ozinsky et al.: "The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5." in: Nature, Vol. 410, Issue 6832, pp. 1099-103, 2001 (PubMed).

Janeway, Medzhitov: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, 2002 (PubMed).

Takeda, Kaisho, Akira: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, 2003 (PubMed).

Hawn, Verbon, Lettinga et al.: "A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease." in: The Journal of experimental medicine, Vol. 198, Issue 10, pp. 1563-72, 2003 (PubMed).

McGettrick, ONeill: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, 2004 (PubMed).