Toll-Like Receptor 6 (TLR6) (N-Term) antibody

Antigen: Toll-Like Receptor 6 (TLR6)

Synonyms: CD286, TLR6, TLR1, TLR1LA

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN238223

Additional Information

Immunogen: Synthetic peptide corresponding to 15 amino acids near the amino terminus of Human TLR6 (Genbank accession No. NP_006059).

Format: Liquid

Description: Rabbit anti TLR6, N-term. Rabbit Antibody to Human Toll-like Receptor 6 (TLR6), N-terminal

Specificity: Reacts with human and mouse TLR6. Does not react with TLR1.

Application Details

Application Notes: Suitable for use in Western blot (1 ? 2ug/ml) and Immunohistochemistry (10ug/ml). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Concentration: Lot specific

Purification: Immunoaffinity purified

Buffer: PBS. Preservative: 0.02% Sodium Azide

Storage: Store (up to one year) at 2-8°C. : This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.

Restrictions: For Research Use only

Publications

Takeuchi, Kawai, Sanjo et al.: "TLR6: A novel member of an expanding toll-like receptor family." in: Gene, Vol. 231, Issue 1-2, pp. 59-65, 1999 (PubMed).

Ozinsky, Underhill, Fontenot et al.: "The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 25, pp. 13766-71, 2000 (PubMed).

Janeway, Medzhitov: "Innate immune recognition." in: Annual review of immunology, Vol. 20, pp. 197-216, 2002 (PubMed).

Takeda, Kaisho, Akira: "Toll-like receptors." in: Annual review of immunology, Vol. 21, pp. 335-76, 2003 (PubMed).

Into, Kiura, Yasuda et al.: "Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation." in: Cellular microbiology, Vol. 6, Issue 2, pp. 187-99, 2004 (PubMed).

McGettrick, ONeill: "The expanding family of MyD88-like adaptors in Toll-like receptor signal transduction." in: Molecular immunology, Vol. 41, Issue 6-7, pp. 577-82, 2004 (PubMed).