TRAF Family Member-Associated NFKB Activator (TANK) (C-Term) antibody

Details for Product No. ABIN238232
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Antigen
Epitope
C-Term
(17), (15), (7), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(84), (37), (37), (2), (2), (2)
Host
Rabbit
(79), (3), (3), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(76), (29), (22), (16), (10), (9), (9), (7), (6), (5), (3), (3), (3)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN238232
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Immunogen Synthetic peptide corresponding to 14 AA near the carboxy terminal of human TANK (Genbank accession No. NP_004171)
Specificity Reacts with the C-terminus of human, mouse, and rat TANK. TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction (1,2). Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. At least 2 isoforms of TANK are known to exist.
Characteristics Rabbit anti TANK (CT), Rabbit antibody to TRAF family member-associated NF-kappaB activator (TANK), C-terminal
Purification Immuno Affinity Chromatography
Alternative Name TRAF family member-associated NF-kappaB activator (TANK)
Application Notes Suitable for use in Western blot (1-2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02 % Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8 °C.
Expiry Date 12 months
General Cheng, Baltimore: "TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation." in: Genes & development, Vol. 10, Issue 8, pp. 963-73, 1996 (PubMed).

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