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Details for Product No. ABIN238232

TRAF Family Member-Associated NFKB Activator (TANK) (C-Term) antibody

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Antigen
Synonyms I-TRAF, ITRAF, TRAF2, C86182, E430026L09Rik
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN238232
Quantity 100 µg
Price
474.47 $   Plus shipping costs $45.00
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Availability Will be delivered in 4 to 5 Business Days
Immunogen Synthetic peptide corresponding to 14 AA near the carboxy terminal of human TANK (Genbank accession No. NP_004171)
Specificity Reacts with the C-terminus of human, mouse, and rat TANK. TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction (1,2). Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-kappaB. At least 2 isoforms of TANK are known to exist.
Characteristics Rabbit anti TANK (CT), Rabbit antibody to TRAF family member-associated NF-kappaB activator (TANK), C-terminal
Purification Immuno Affinity Chromatography
Alternative Name TRAF family member-associated NF-kappaB activator (TANK)
Application Notes Suitable for use in Western blot (1-2 µg/mL). Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Format Liquid
Buffer PBS, 0.02% Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide, which has been classified as Xn (Harmful) in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Storage 4 °C
Storage Comment Store (up to one year) at 2-8°C.
Expiry Date 12 months
Cheng, Baltimore: "TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation." in: Genes & development, Vol. 10, Issue 8, pp. 963-73, 1996 (PubMed).

Alternatives for antigen "TRAF Family Member-Associated NFKB Activator (TANK)", type "Antibodies"
Hosts (68), (4), (3), (1)
Reactivities (74), (37), (36), (3), (2), (1), (1), (1), (1), (1)
Applications (66), (24), (20), (13), (10), (9), (8), (6), (3), (3), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (15), (12), (5), (4), (2), (2), (1), (1), (1), (1)
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