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Details for Product No. ABIN238326

Ribonucleoprotein, PTB-Binding 1 (RAVER1) antibody

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Antigen
Synonyms 1300006N24Rik, AA050359, mKIAA1978, Raver1h, MGC83237, zgc:112236, RAVER1
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus)
Host
»Alternatives Mouse
Clonality Monoclonal
Application
»Alternatives Western Blotting (WB), Immunofluorescence (IF)
Pubmed 3 references available
Catalog no. ABIN238326
Quantity 100 µg
Price
638.88 $   Plus shipping costs $45.00
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Availability Will be delivered in 5 to 6 Business Days
Immunogen N-terminal Raver-1 fragment (Aminoacids 1-625) with MBP
Isotype IgG1, kappa chain
Specificity Epitope: E-T-V-D-R-R
Purification Fusion partner: Balb/c Myeloma, non secretor, NS 0/1. Immune animal: Balb/c mice
Alternative Name Raver-1
Background Raver-1 may play an important role for the regulation of neuronal synaptic plasticity, possibly by controlling especially the late LTP via posttranscriptional mechanisms. PTB-mediated splicing repression involves recruitment of Raver-1 as a potent splicing co-repressor. Synonyms: ribonucleoprotein, PTB-binding 1. Other Designations: AA050359, KIAA1978, MGC118403, mKIAA1978, 1300006N24Rik
Gene ID 71766
Research Area DNA/RNA
Application Notes Immunoblot: 1:100 . Heart (Mouse): 80kDa band. Brain (Mouse): 80kDa band. C2C12 (rat): 80kDa band. PAC 1 (rat): 80kDa band. PC 12 (rat): 80kDa band. Immunofluorescence: 1:50 to 1:100. Fixation: 4% formaldehyde, 20 minutes. Extraction: 0,2% Triton X-100, 10 minutes. Positive results for C2C12 cells.
Restrictions For Research Use only
Format Liquid
Concentration 10 µg/ml (Charge 02/06, tissue supernatant)
Storage -20 °C
Huettelmaier, Illenberger, Grosheva et al.: "Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins." in: The Journal of cell biology, Vol. 155, Issue 5, pp. 775-86, 2001 (PubMed).

Gromak, Rideau, Southby et al.: "The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing." in: The EMBO journal, Vol. 22, Issue 23, pp. 6356-64, 2003 (PubMed).

Zieseniss, Schroeder, Buchmeier et al.: "Raver1 is an integral component of muscle contractile elements." in: Cell and tissue research, Vol. 327, Issue 3, pp. 583-94, 2007 (PubMed).

Alternatives for antigen "Ribonucleoprotein, PTB-Binding 1 (RAVER1)", type "Antibodies"
Hosts (11), (2)
Reactivities (8), (2), (2), (2), (1)
Applications (12), (4), (2), (1), (1)
Epitopes (6), (2), (2), (1), (1)
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