Ribonucleoprotein, PTB-Binding 1 (RAVER1) antibody

Antigen: Ribonucleoprotein, PTB-Binding 1 (RAVER1)

Synonyms: KIAA1978, AA050359, MGC118403, mKIAA1978, 1300006N24Rik, Raver1h, MGC83237, MGC112236, zgc:112236, RAVER1, MGC139960

Clonality: Monoclonal (5G6)

Host: Mouse

Reactivity: Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB), Immunofluorescence (IF)

Catalog no.: ABIN238326

Additional Information

Alternative name: Raver-1

Gene ID: 71766

Immunogen: N-terminal Raver-1 fragment (Aminoacids 1-625) with MBP

Format: Supernatant

Isotype: IgG1, kappa chain

Clone: 5G6

Description: Raver-1 may play an important role for the regulation of neuronal synaptic plasticity, possibly by controlling especially the late LTP via posttranscriptional mechanisms. PTB-mediated splicing repression involves recruitment of Raver-1 as a potent splicing co-repressor. Synonyms: ribonucleoprotein, PTB-binding 1. Other Designations: AA050359, KIAA1978, MGC118403, mKIAA1978, 1300006N24Rik

Specificity: Epitope: E-T-V-D-R-R

Application Details

Application Notes: Immunoblot: 1:100 . Heart (Mouse): 80kDa band. Brain (Mouse): 80kDa band. C2C12 (rat): 80kDa band. PAC 1 (rat): 80kDa band. PC 12 (rat): 80kDa band. Immunofluorescence: 1:50 to 1:100. Fixation: 4% formaldehyde, 20 minutes. Extraction: 0,2% Triton X-100, 10 minutes. Positive results for C2C12 cells.

Concentration: 10 µg/ml (Charge 02/06, tissue supernatant)

Purification: Fusion partner: Balb/c Myeloma, non secretor, NS 0/1. Immune animal: Balb/c mice

Storage: Store at -20 C

Research Area: DNA/RNA

Restrictions: For Research Use only

Images

anti-Ribonucleoprotein, PTB-Binding 1 (RAVER1) antibody

Publications

Huettelmaier, Illenberger, Grosheva et al.: "Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins." in: The Journal of cell biology, Vol. 155, Issue 5, pp. 775-86, 2001 (PubMed).

Gromak, Rideau, Southby et al.: "The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing." in: The EMBO journal, Vol. 22, Issue 23, pp. 6356-64, 2003 (PubMed).

Zieseniss, Schroeder, Buchmeier et al.: "Raver1 is an integral component of muscle contractile elements." in: Cell and tissue research, Vol. 327, Issue 3, pp. 583-94, 2007 (PubMed).