ACPP antibody

Catalog No. ABIN238332

Product Details anti-ACPP Antibody

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ACPP antibody is un-conjugated

Application: Flow Cytometry (FACS), Cell-ELISA (cELISA)

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human PAP

Clone: LT-3D1

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Restrictions: For Research Use only

Handling

Concentration: 2 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

Target Details for ACPP

Target: ACPP (Acid Phosphatase, Prostate (ACPP))

Alternative Name: PAP (ACPP Products)

Background: Human prostatic acid phosphatase (PAP) is a non-specific phosphomonoesterase, synthesised and secreted into seminal plasma under androgenic control. Human PAP is a 100 kDa glycoprotein containing two subunits of approximately 50 kDa each. It catalyses the dephosphorylation of organic monophosphate esters, demonstrating optimum activity at an acid pH. Produced by the prostatic epithelium, serum levels of PAP are very low in healthy individuals, but are often elevated in malignant and benign prostatic disease while it has been used as a marker of diagnosis and therapy control of cancer of the prostate gland.

UniProt: P15309

Pathways: Synaptic Membrane, Ribonucleoside Biosynthetic Process