C-Src tyrosine Kinase (CSK) antibody

Antigen: C-Src tyrosine Kinase (CSK)

Synonyms: MGC117393, AW212630, MGC112926

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN238342

Additional Information

Characteristics: Synonyms: Tyrosine-protein kinase CSK, C-SRC kinase, Protein-tyrosine kinase CYL

Alternative name: CSK

Swiss-Prot: P41240

Immunogen: Bacterially expressed recombinant protein corresponding to C-terminal part (residues330-450) of Csk.

Cross-Reactivity: Human

Description: C-terminal Src kinase (Csk) is a non-receptor protein tyrosine kinase. One of its majorfunctions is to specifically phosphorylate a conserved C-terminal tyrosine of Src familykinases thereby down-regulating their kinase activity. CSK is expressed ubiquitously as aprotein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due tointeraction with the lipid raft-associated protein PAG (Csk-binding protein).

Specificity: The polyclonal antibody detects total level of endogenous Csk protein. Species: Human. Others not tested.

Application Details

Application Notes: Western Blotting. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 1.0 mg/ml

Purification: Aff - Purified

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Research Area: Signaling, Tyrosine Kinases

Restrictions: For Research Use only