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Syndecan 1 (SDC1) antibody
| Antigen | Syndecan 1 (SDC1) |
| Synonyms | SDC, CD138, SYND1, syndecan, Sstn, Synd, Synd1, syn-1, AA408134, AA409076, sdc, Syn1, cd138, synd1, xSyn1, syndecan1, Syndecan-1, XSyndecan-1, HSPG, SYNDECA, Syndecan, SDC1, MGC139976 |
| Clonality | Monoclonal (B-A38) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
|
| Catalog no. | ABIN238385 |
| Quantity | 0.1 mg (1.0 mg/ml) |
| Price | 270.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: SYND1, SDC1, SDC |
| Alternative name | CD138 / Syndecan-1 |
| Swiss-Prot | P18827 |
| Immunogen | U266 human peripheral blood myeloma cell line |
| Cross-Reactivity | Human |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | B-A38 |
| Description | CD138 (syndecan-1) is a transmembrane proteoglycan that can bind a variety of cytokinesand modulate their activity, as well as the activity of extracellular matrix components andinfluence many developmental processes. CD138 is expressed mainly in differentiatingkeratinocytes and is transiently upregulated in all layers of the epidermis upon tissueinjury. It is also highly expressed on plasma cells and can be detected even on fibroblasts,vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation ofCD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor ofcancerogenesis. |
| Specificity | The antibody B-A38 recognizes CD138 (syndecan-1), a 65-70 kDa heparan sulfateproteoglycan expressed mainly in the epidermis and plasma cells, but also in growthfactor-stimulated lymphocytes. Species: Human. Others not tested. |
Application Details
| Application Notes | Suitable for Flow Cytometry and Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Concentration | 1.0 mg/ml |
| Purification | Azide Free |
| Buffer | PBS, pH 7.4 without preservatives |
| Storage | Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Syndecan 1 (SDC1)", type "Antibodies"
| Hosts | Mouse (32), Rabbit (9) |
| Reactivities | Human (39), Hamster (3), Mouse (Murine) (2), Rat (Rattus) (2) |
| Applications | Flow Cytometry (FACS) (26), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Western Blotting (WB) (15), Immunohistochemistry (Frozen Sections) (IHC (fro)) (9), ELISA (6), Immunocytochemistry (ICC) (6), Immunohistochemistry (IHC) (3), Immunoprecipitation (IP) (3), Enzyme Immunoassay (EIA) (1) |
| Conjugates | FITC (5), PE (2), APC (1), Alexa Fluor 700 (1), PerCP (1), PerCP,Cy5.5 (1), RPE (1) |
| Epitopes | C-Term (1) |
