»
Antibodies
»
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
| Antigen |
|
| Synonyms |
LAMPA, CD107a, LGP120 |
| Clonality |
Monoclonal (B-T47) |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
Flow Cytometry (FACS) (70), Western Blotting (WB) (36), Immunoprecipitation (IP) (23), Immunohistochemistry (Frozen Sections) (IHC (fro)) (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunofluorescence (IF) (10), Immunocytochemistry (ICC) (8), Immunohistochemistry (IHC) (5), ELISA (2), ELISA (Detection) (2), Enzyme Immunoassay (EIA) (2), Immunoelectron Microscopy (EM) (1)
|
| Catalog no. |
ABIN238392 |
| Quantity |
0.1 mg (1.0 mg/ml) |
| Price |
270.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Characteristics
|
Synonyms: LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1, CD107Antigen-like Family Member A
|
|
Alternative name
|
CD107a / LAMP1
|
|
Swiss-Prot
|
P11279
|
|
Immunogen
|
U937 human Caucasian hystiocytic lymphoma cell line.
|
|
Cross-Reactivity
|
Human
|
|
Isotype
|
IgG1 (Matching secondary antibodies)
|
|
Clone
|
B-T47
|
|
Description
|
CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is amajor constituent of lysosomal membrane, 1-2% of total CD107a is found also on theplasma membrane. The LAMP proteins are involved in lysosome biogenesis and arerequired for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity isobserved in neurones, and in glial cells surrounding senile plaques in Alzheimers diseasecases and is localized mainly in medullary epithelial cells, single macrophages andlymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.
|
|
Specificity
|
The antibody B-T47 recognizes CD107a, a 100-120 kDa glycoprotein expressed mainly onlysosomal, but also on the plasma membrane. Species: Human. Others not tested.
|
|
Application Notes
|
Suitable for Flow Cytometry and Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Concentration
|
1.0 mg/ml
|
|
Purification
|
Azide Free
|
|
Buffer
|
PBS, pH 7.4 without preservatives.
|
|
Storage
|
Store the antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
|
|
Research Area
|
CD Antigens, Surface Receptors of Immune Cells
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Lysosomal-Associated Membrane Protein 1 (LAMP1)", type "Antibodies"
|
Hosts
|
Mouse (61), Rat (24), Rabbit (12)
|
|
Reactivities
|
Human (58), Mouse (Murine) (30), Rat (Rattus) (13), Pig (Porcine) (6), Hamster (5), Primate (2)
|
|
Applications
|
Flow Cytometry (FACS) (70), Western Blotting (WB) (36), Immunoprecipitation (IP) (23), Immunohistochemistry (Frozen Sections) (IHC (fro)) (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Immunofluorescence (IF) (10), Immunocytochemistry (ICC) (8), Immunohistochemistry (IHC) (5), ELISA (2), ELISA (Detection) (2), Enzyme Immunoassay (EIA) (2), Immunoelectron Microscopy (EM) (1)
|
|
Conjugates
|
FITC (14), PE (14), APC (10), Biotin (8), Cy5,PE (3), SPRD (2), Alexa Fluor 488 (1), RPE (1)
|
|
Epitopes
|
C-Term (1), N-Term (1)
|
