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CD14 Molecule (CD14) antibody

Antigen

CD14 Molecule (CD14)
Synonyms CD14
Clonality Monoclonal (MEM-18)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Catalog no. ABIN238457
Quantity 0.1 mg  (1.0 mg/ml)  (Variants)
Price 540.00 $   Plus shipping costs $35.00
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Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Alternative name CD14
Modification F(ab')2 fragement
Swiss-Prot P08571
Immunogen A crude mixture of human urinary proteins precipitated by ammonium sulphate from the urine of a patient suffering from proteinuria
Cross-Reactivity Human, Monkey
Isotype IgG1  (Matching secondary antibodies)
Clone MEM-18
Description CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor, it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
Specificity The antibody MEM-18 reacts with CD14, a 53-55 kDa GPI (glycosylphosphatidylinositol)-linked membrane glycoprotein expressed on monocytes, macrophages and weakly on granulocytes, also expressed by most tissue macrophages. In human, the epitope recognized by MEM-18 is located between amino acids 57-64.

Application Details
Alternatives Secondary Antibodies Variants back to top

Concentration 1.0 mg/ml
Purification Aff - Purified
Buffer PBS, pH 7.4 without preservatives.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid freeze/thaw cycles. Shelf Life: One year from despatch.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "CD14 Molecule (CD14)", type "Antibodies"
Hosts Mouse (241), Rabbit (36), Goat (8), Rat (2), Chicken (1)
Reactivities Human (266), Pig (Porcine) (34), Mouse (Murine) (30), Cow (Bovine) (28), Dog (Canine) (26), Sheep (Ovine) (25), Rabbit (24), Monkey (23), Primates (19), Rat (Rattus) (18), Goat (9), Cat (Feline) (8), Primate (8), Chicken (1), Llama (1)
Applications Flow Cytometry (FACS) (218), Western Blotting (WB) (55), ELISA (37), Immunoprecipitation (IP) (32), Functional Studies (Func) (25), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (24), Immunohistochemistry (Frozen Sections) (IHC (fro)) (22), Immunofluorescence (IF) (20), Enzyme Immunoassay (EIA) (19), Immunohistochemistry (IHC) (16), ELISA (Detection) (5), Blocking Antibody (Inhibition) (3), Immunocytochemistry (ICC) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1), Radioimmunoassay (RIA) (1)
Conjugates FITC (35), PE (24), Biotin (21), APC (16), RPE (8), Cy5.5 (5), Alexa Fluor 488 (3), Pacific Blue (3), Alexa Fluor 700 (2), Cy5 (2), Cy7,PE (2), PE,Cy5 (2), PE,Cy7 (2), PE,DY590 (2), PE,DY647 (2), SPRD (2), APC,Cy7 (1), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), CF (1), Cy3 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5.5 (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), PerCP (1), RBITC (1), RPE,Cy5 (1), RPE,Cy5.5 (1)
Epitopes C-Term (2), N-Term (2)