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Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C) antibody

Antigen

Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C)
Synonyms LIT, DCR1, TRID, CD263, TRAILR3, MGC149501, MGC149502, Dicer, HERNA, KIAA0928, TNFRSF10C
Clonality Monoclonal (TRAIL-R3-02)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Flow Cytometry (FACS)
Catalog no. ABIN238512
Quantity 0.1 mg  (1.0 mg/ml)
Price 290.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Characteristics Synonyms: Decoy receptor 1, TNFRSF10C, DCR1, LIT, TRID, TRAIL receptor 3, TRAIL-R3, Tumor necrosisfactor receptor superfamily member 10C, Decoy TRAIL receptor without death domain,TNF-related apoptosis-inducing ligand receptor 3, Trail receptor without an intracellulardomain, Lymphocyte inhibitor of TRAIL, Antagonist decoy receptor for TRAIL/Apo-2L
Alternative name CD263 / TRAILR3
Swiss-Prot O14798
Immunogen TRAIL-R3 (aa 1-280) - hIgGhc fusion protein.
Cross-Reactivity Human
Isotype IgG1  (Matching secondary antibodies)
Clone TRAIL-R3-02
Description TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs toreceptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in manytumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein thatlacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as anegative regulator of apoptotic signaling by competing for binding of TRAIL with deathreceptor 5 (DR5).
Specificity The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellularmembrane protein expressed mainly on neutrophils. Species: Human. Others not tested.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes Suitable for Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Azide Free
Buffer PBS, pH 7.4 without preservatives.
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Research Area Signaling, Apoptosis/Necrosis
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "Tumor Necrosis Factor Receptor Superfamily, Member 10c, Decoy Without An Intracellular Domain (TNFRSF10C)", type "Antibodies"
Hosts Mouse (19), Rabbit (10), Goat (1)
Reactivities Human (28), Mouse (Murine) (5), Rat (Rattus) (5)
Applications Flow Cytometry (FACS) (19), Western Blotting (WB) (13), Immunofluorescence (IF) (5), Immunoprecipitation (IP) (4), Enzyme Immunoassay (EIA) (2), ELISA (Detection) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
Conjugates FITC (4), PE (4)