TAK1-Binding Protein 3 (MAP3K7IP3) (AA 274-285) antibody

Antigen: TAK1-Binding Protein 3 (MAP3K7IP3)

Synonyms: NAP1, TAB3, MGC45404, KIAA4135, Map3k7ip3, mKIAA4135, RP23-181A7.1, 4921526G09Rik, tab3, map3k7ip3, si:dkey-30h22.6, si:ch211-232d19.8

Epitope: AA 274-285

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN238574

Additional Information

Alternative name: MAP3K7IP3 (aa 274 to 285)

Gene ID: 257397, 66724 (mouse)

Immunogen: C-NYQPSQYSPKQQ

Format: Affinity-purified

Description: All names and symbols: MAP3K7IP3, mitogen-activated protein kinase kinase kinase 7 interacting protein 3, MGC45404, NAP1, TAB3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAK1 bindi. Official Symbol: MAP3K7IP3 . RefSeq number(s): NP_690000.2

Specificity: Human, Mouse

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:8,000. Western Blot: Preliminary experiments gave an approx 48kDa band in Human Kidney lysates after 0.3µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 78.7kDa according to NP_690000.2. The 48kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Publications

Publications: Lu, Lin, Huang et al.: "XIAP induces NF-kappaB activation via the BIR1/TAB1 interaction and BIR1 dimerization." in: Molecular cell, Vol. 26, Issue 5, pp. 689-702, 2007 (PubMed).