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Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (Internal Region) antibody

Details for Product No. ABIN238578, Supplier: Log in to see
Antigen
  • Kcc3
  • ACCPN
  • KCC3
  • KCC3A
  • KCC3B
  • 9530023I19Rik
  • gaxp
Epitope
Internal Region
17
15
11
5
2
2
1
1
1
Reactivity
Human
58
23
22
1
1
1
1
1
Host
Goat
48
10
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
43
29
28
11
6
2
1
1
Supplier
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Immunogen Peptide with sequence SRHIDVCSKTKE, from the internal region of the protein sequence according to NP_001035959.1, NP_001035960.1, NP_001035961.1, NP_001035962.1, NP_005126.1, NP_598408.1.
Blocking Peptide Blocking peptide for this product available: ABIN370465
Specificity This antibody is expected to recognise all 6 reported isofoms (NP_598408.1, NP_005126.1, NP_001035959.1, NP_001035960.1, NP_001035961.1, NP_001035962.1, ),
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name KCC3 / SLC12A6 (SLC12A6 Antibody Abstract)
Background Synonyms: SLC12A6, KCC3, solute carrier family 12 (potassium/chloride transporters), member 6, ACCPN, DKFZP434D2135, KCC3A, KCC3B, agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome), potassium chloride cotransporter 3, potassium chloride c
Gene ID 9990
NCBI Accession NP_001035959, NP_005126, NP_001035961, NP_001035962, NP_598408, NP_001035960
Pathways
Application Notes ELISA: antibody detection limit dilution 1:16000.
Western blot: Approx 120 kDa band observed in Human Heart and Kidney lysates (calculated MW ranging 121-128 kDa according to NP_598408.1, NP_005126.1, NP_001035959.1, NP_001035960.1, NP_001035961.1, NP_001035962.1). Recommended concentration: 0.1-0.3 µg/mL.
IHC: In paraffin embedded Human Heart shows staining of myocardial fibrils in transverse section. Recommended concentration: 2-4 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-Solute Carrier Family 12 (Potassium-Chloride Transporter) Member 6 (SLC12A6) (Internal Region) antibody (ABIN238578) ABIN238578 (0.1µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). P...
Background publications Simard, Bergeron, Frenette-Cotton et al.: "Homooligomeric and heterooligomeric associations between K+-Cl- cotransporter isoforms and between K+-Cl- and Na+-K+-Cl- cotransporters." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18083-93, 2007 (PubMed).

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