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SRY (Sex Determining Region Y)-Box 17 (SOX17) (Internal Region) antibody

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Synonyms sox17, Xsox17, sox17beta, sox17-beta, tSox17beta, Xsox17-beta, SOX17, Sox17alpha, Xsox17-alpha, Xsox17alpha, sox17-alpha, tSox17alpha, xSox17alpha1, xSox17alpha2, xsox17a, sox7/17, VUR3, Sox
Internal Region
(25), (17), (8), (4), (4), (2), (2), (1), (1), (1)
Human, Rat (Rattus)
(69), (16), (7), (6), (3), (3), (3), (1), (1), (1)
(31), (27), (19)
(3), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
ELISA, Western Blotting (WB)
(45), (32), (17), (9), (8), (7), (6), (6), (3), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 100 μg
Shipping to United States ( )
Availability Available
Immunogen Peptide with sequence EALPCRDGTDP, from the internal region of the protein sequence according to NP_071899.1.
Blocking Peptide Blocking peptide for this product available: ABIN370105
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name SOX17 (SOX17 Antibody Abstract)
Background Synonyms: SRY (sex determining region Y)-box 17, FLJ22252, SRY-box 17, SRY-related HMG-box transcription factor SOX17
Gene ID 64321, 312936
NCBI Accession NP_071899
Research Area Embryogenesis, Embryonic stem cells, Transcription Factors
Application Notes ELISA: antibody detection limit dilution 1:32000.
Western blot: Preliminary experiments gave an approx 20 kDa band in Rat Brain and Rat Spinal Cord lysates after 1 µg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 44.6 kDa according to Mouse NP_035571.1 and of 44.1 kDa according to Human NP_071899.1. The 20 kDa band was successfully blocked by incubation with the immunizing peptide.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Background publications Kim, Saunders, Morrison: "Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells." in: Cell, Vol. 130, Issue 3, pp. 470-83, 2007 (PubMed).

Catalog No. ABIN238613
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