SRY (Sex Determining Region Y)-Box 17 (SOX17) antibody
| Antigen | SRY (Sex Determining Region Y)-Box 17 (SOX17) |
| Synonyms |
MGC91776, FLJ22252, sox17, Xsox17, sox17beta, sox17-beta, tSox17beta, Xsox17-beta, SOX17, xsox17a, Sox17alpha, sox17-alpha, tSox17alpha, Xsox17-alpha, xSox17alpha1, xSox17alpha2, sox17a, xsox17, sox17 ...
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| Clonality | Polyclonal |
| Host |
 Alternatives Goat |
| Reactivity | |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives ELISA |
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1 reference available |
| Catalog no. | ABIN238613 |
| Quantity | 100 ug |
| Price | 261.61 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Ships within 5 Business Days |
Additional Information
| Alternative name | SOX17 |
| Gene ID | 64321, 312936 (rat) |
| Immunogen | EALPCRDGTDP |
| Description | All names and symbols: SRY (sex determining region Y)-box 17, FLJ22252, SRY-box 17, SRY-related HMG-box transcription factor SOX17. Official Symbol: SOX17. RefSeq number(s): NP_071899.1 |
| Specificity | Human, Rat |
| Synonyms | MGC91776, FLJ22252, sox17, Xsox17, sox17beta, sox17-beta, tSox17beta, Xsox17-beta, SOX17, xsox17a, Sox17alpha, sox17-alpha, tSox17alpha, Xsox17-alpha, xSox17alpha1, xSox17alpha2, sox17a, xsox17, sox17a1, MGC131036, xsox17-alpha, sox17b, sox17b.1, Sox17beta, XSox17beta, xsox17-beta, sox17a2, MGC68799, Xsox17alpha, sox17b.3, sox7/17 |
Application Details
| Application Notes | Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Preliminary experiments gave an approx 20kDa band in Rat Brain and Rat Spinal Cord lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 44.6kDa according to Mouse NP_035571.1 and of 44.1kDa according to Human NP_071899.1. The 20kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported? |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Storage | Aliquot and store at -20°C. Minimize freezing and thawing. |
| Research Area | Embryogenesis, Embryonic stem cells, Transcription Factors |
| Restrictions | For Research Use only |
Publications
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Kim, Saunders, Morrison: "Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells." in: Cell, Vol. 130, Issue 3, pp. 470-83, 2007 (PubMed).
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Alternatives
Alternatives for antigen "SRY (Sex Determining Region Y)-Box 17 (SOX17)", type "Antibodies"
| Hosts | Rabbit (28), Mouse (17), Goat (5) |
| Reactivities | Human (49), Mouse (Murine) (22), Rat (Rattus) (20), Dog (Canine) (3), Chicken (2), Monkey (2), Opossum (Didelphimorphia) (2), Cow (Bovine) (1), Pig (Porcine) (1), Zebrafish (1), Zebrafish (Danio rerio) (1) |
| Applications | Immunofluorescence (IF) (25), Western Blotting (WB) (25), ELISA (11), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Flow Cytometry (FACS) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1) |
| Conjugates | APC (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1) |
| Epitopes | AA 177-414 (13), AA 120-170 (2), AA 70-120 (2), Internal Region (2), C-Term (1) |
