Cysteine-S-conjugate beta-Lyase (CCBL1) antibody

Antigen: Cysteine-S-conjugate beta-Lyase (CCBL1)

Synonyms: GTK, KAT1, KATI, FLJ95217, MGC29624

Clonality: Polyclonal

Host: Goat

Application: ELISA

Catalog no.: ABIN238642

Additional Information

Alternative name: CCBL1

Gene ID: 883

Immunogen: C-DISDFKRKMPD

Format: Affinity-purified

Description: All names and symbols: CCBL1, cysteine conjugate-beta lyase, glutamine transaminase K, kyneurenine aminotransferase, GTK, KATI, MGC29624, cytoplasmic cysteine conjugate-beta lyase, glutamine-phenylpyruvate aminotransferase, kynurenine aminotransferase I. Official Symbol: CCBL1. RefSeq number(s): NP_004050.3, NP_001116144.1

Specificity: This antibody is expected to recognize both reported isoforms (NP_004050.3, NP_001116144.1) Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Preliminary experiments in Human Brain (Cerebral and frontal cortex) and Human Breast cancer lysates gave no specific signal but low background (at antibody concentration up to 1µg/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Research Area: Signaling, Metabolism, Amino Acids

Restrictions: For Research Use only

Publications

Publications: Cooper: "The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants." in: Neurochemistry international, Vol. 44, Issue 8, pp. 557-77, 2004 (PubMed).