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LTB antibody

LTB Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2427427
  • Target See all LTB Antibodies
    LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
    Reactivity
    • 33
    • 26
    • 14
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Human, Mouse
    Host
    • 47
    • 4
    • 2
    Rabbit
    Clonality
    • 47
    • 6
    Polyclonal
    Conjugate
    • 25
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LTB antibody is un-conjugated
    Application
    • 40
    • 21
    • 7
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human LTB
    Isotype
    IgG
    Top Product
    Discover our top product LTB Primary Antibody
  • Application Notes
    IHC 1:30-1:150
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.9 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
    Alternative Name
    LTB (LTB Products)
    Synonyms
    AI662801 antibody, LTbeta antibody, Tnfc antibody, Tnfsf3 antibody, p33 antibody, TNFC antibody, TNFSF3 antibody, LT-b antibody, LT-beta antibody, TNF-C antibody, lymphotoxin B antibody, lymphotoxin beta antibody, Ltb antibody, LTB antibody
    Background
    Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
    NCBI Accession
    NP_002332
    Pathways
    NF-kappaB Signaling
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