AMZ2 antibody

Catalog No. ABIN2429233

Product Details anti-AMZ2 Antibody

Target: AMZ2 (Archaelysin Family Metallopeptidase 2 (AMZ2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMZ2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human AMZ2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AMZ2

Target: AMZ2 (Archaelysin Family Metallopeptidase 2 (AMZ2))

Alternative Name: AMZ2 (AMZ2 Products)

Synonyms: AA408420 antibody, ESTM12 antibody, X83328 antibody, RGD1304846 antibody, archaelysin family metallopeptidase 2 antibody, AMZ2 antibody, Amz2 antibody

Background: AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.