FAM107A antibody

Catalog No. ABIN2430061

Product Details anti-FAM107A Antibody

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM107A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human FAM107A

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAM107A

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Alternative Name: FAM107A (FAM107A Products)

Synonyms: drr1 antibody, tu3a antibody, xdrr1 antibody, DRR1 antibody, TU3A antibody, Drr1 antibody, RGD1306327 antibody, Tu3a antibody, family with sequence similarity 107 member A S homeolog antibody, family with sequence similarity 107 member A antibody, family with sequence similarity 107, member A antibody, fam107a.S antibody, FAM107A antibody, Fam107a antibody

Background: FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5 % of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.