MT3 antibody
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- Target See all MT3 Antibodies
- MT3 (Metallothionein 3 (MT3))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MT3 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human MT3
- Isotype
- IgG
- Top Product
- Discover our top product MT3 Primary Antibody
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- Application Notes
- IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Handling Advice
- Avoid freeze / thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MT3 (Metallothionein 3 (MT3))
- Alternative Name
- MT3 (MT3 Products)
- Synonyms
- MT1 antibody, GIF antibody, GIFB antibody, GRIF antibody, ZnMT3 antibody, Mt-3 antibody, MT-III antibody, ATMT3 antibody, metallothionein 3 antibody, MT3 antibody, MT-3 antibody, metallothionein 3 antibody, MT3 antibody, Mt3 antibody
- Background
- Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease.
- Pathways
- Hormone Transport, Transition Metal Ion Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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