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Necdin-Like 2 antibody

NDNL2 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2432595
  • Target See all Necdin-Like 2 (NDNL2) Antibodies
    Necdin-Like 2 (NDNL2)
    Reactivity
    • 13
    • 12
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 12
    • 1
    Rabbit
    Clonality
    • 12
    • 1
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Necdin-Like 2 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human NDNL2
    Isotype
    IgG
    Top Product
    Discover our top product NDNL2 Primary Antibody
  • Application Notes
    WB 1:1000-1:5000, IHC 1:50-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.4 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Necdin-Like 2 (NDNL2)
    Alternative Name
    NSMCE3 (NDNL2 Products)
    Synonyms
    mage antibody, zgc:101850 antibody, NDNL2 antibody, HCA4 antibody, MAGEG1 antibody, MAGEL3 antibody, NSE3 antibody, NSMCE3 antibody, 5730494G16Rik antibody, AI642138 antibody, BB044375 antibody, Mageg1 antibody, mage-g1 antibody, NSE3 homolog, SMC5-SMC6 complex component antibody, necdin-like 2 antibody, Nsmce3 antibody, ndnl2 antibody, NDNL2 antibody, NSMCE3 antibody
    Background
    The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).
    Molecular Weight
    Calculated MW: 34 kDa
    NCBI Accession
    NP_619649
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