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CHRNA2 antibody

CHRNA2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2432845
  • Target See all CHRNA2 Antibodies
    CHRNA2 (Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2))
    Reactivity
    • 26
    • 2
    • 1
    Human
    Host
    • 26
    • 2
    Rabbit
    Clonality
    • 27
    • 1
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRNA2 antibody is un-conjugated
    Application
    • 21
    • 16
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human CHRNA2
    Isotype
    IgG
    Top Product
    Discover our top product CHRNA2 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:25-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CHRNA2 (Cholinergic Receptor, Nicotinic, alpha 2 (Neuronal) (CHRNA2))
    Alternative Name
    CHRNA2 (CHRNA2 Products)
    Synonyms
    CHRNA2 antibody, NACHRA2 antibody, chrna2 antibody, zgc:136717 antibody, ACHR antibody, Acra-2 antibody, Acra2 antibody, BC011490 antibody, cholinergic receptor nicotinic alpha 2 subunit antibody, cholinergic receptor, nicotinic, alpha 2a (neuronal) antibody, cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) antibody, neuronal acetylcholine receptor subunit alpha-2 antibody, neuronal acetylcholine receptor subunit alpha-4-like antibody, CHRNA2 antibody, chrna2a antibody, Chrna2 antibody, CpipJ_CPIJ002436 antibody, LOC100370261 antibody, Tsp_10995 antibody
    Background
    Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.
    Molecular Weight
    Calculated MW: 60 kDa
    NCBI Accession
    NP_000733
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