IL12RB2 antibody

Catalog No. ABIN2433183

Product Details anti-IL12RB2 Antibody

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL12RB2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Synthetic peptide of human IL12RB2

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for IL12RB2

Target: IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))

Alternative Name: IL12RB2 (IL12RB2 Products)

Synonyms: IL12RB2 antibody, A930027I18Rik antibody, IL-12RB2 antibody, Ifnm antibody, interleukin 12 receptor subunit beta 2 antibody, interleukin 12 receptor, beta 2 antibody, IL12RB2 antibody, Il12rb2 antibody

Background: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation.

NCBI Accession: NP_001550

Pathways: JAK-STAT Signaling