TM7SF2 antibody

Catalog No. ABIN2434015

Product Details anti-TM7SF2 Antibody

Target: TM7SF2 (Transmembrane 7 Superfamily Member 2 (TM7SF2))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TM7SF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Synthetic peptide of human TM7SF2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TM7SF2

Target: TM7SF2 (Transmembrane 7 Superfamily Member 2 (TM7SF2))

Alternative Name: TM7SF2 (TM7SF2 Products)

Synonyms: 3110041O18Rik antibody, ANG1 antibody, C14SR antibody, Dhcr14 antibody, DHCR14A antibody, NET47 antibody, zgc:103611 antibody, tm7sf2 antibody, transmembrane 7 superfamily member 2 antibody, transmembrane 7 superfamily member 2 L homeolog antibody, TM7SF2 antibody, Tm7sf2 antibody, tm7sf2 antibody, tm7sf2.L antibody

Background: Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.

Molecular Weight: Calculated MW: 46 kDa

NCBI Accession: NP_003264