NUP153 antibody (Nucleoporin 153kDa) (AA 610-1191)

Details for Product anti-NUP153 Antibody No. ABIN2452062, Supplier: Log in to see
Antigen
  • CG4453
  • Dmel\\CG4453
  • NUP153
  • Nup 153
  • dNup153
  • dmNup153
  • nup153
  • NUCZINK
  • B130015D15Rik
  • C88147
  • HNUP153
  • N153
  • Nucleoporin 153
  • nucleoporin 153kDa
  • nucleoporin 153
  • nucleoporin Nup153
  • Nup153
  • NUP153
  • LOC100232758
  • nup153
Alternatives
anti-Human NUP153 antibody for Immunocytochemistry
Epitope
AA 610-1191
6
4
4
4
3
3
2
1
1
1
Reactivity
Rat (Rattus)
42
12
7
3
2
2
1
1
1
1
1
1
1
Host
Rat
39
5
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
This NUP153 antibody is un-conjugated
2
2
2
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA, Western Blotting (WB)
34
15
14
11
8
7
6
6
3
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Recombinant GST-fused rat Nup153 (610-1191aa, Zn finger and FG repeats domain)
Clone R4C8
Isotype IgG2a kappa
Specificity Specific to human, mouse, rat and monkey Nup153 proteins.
Cross-Reactivity (Details) Not tested for other species
Characteristics When injected into the nucleus,R4C8 accumulates into the nuclear pores of Hela cells. R4C8 works in immuno-cytochemistry very well.
Purification Purified
Sterility Sterile filtered
Alternative Name Nup153 (NUP153 Antibody Abstract)
Background The nuclear pore complex (NPC) regulates cargo transport between the cytoplasm and the nucleus. Nup (Nucleoporin) 153 is a large (153 kDa) O-linked glycoprotein which is a component of the basket structure located on the nucleoplasmic face of NPC. Nup153 plays a critical role in nuclear export of RNA and proteins. The antibody was purified from the serum-free cultured medium of the hybridoma under mild conditions by propriety chromatography processes.
UniProt P49790
Research Area Chromatin and Nuclear Signaling
Pathways Protein targeting to Nucleus
Application Notes 1. Western blotting: 160 kDa single band in Hela cell extract
2. Immunocytochemistry
3. ELISA
Other applications have not been tested.

Additional comments:
When injected into the nucleus, R4C8 accumulates into the nuclear pores of Hela cells.
R4C8 works in immuno-cytochemistry very well.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS, 50 % glycerol
Preservative Azide free
Storage -20 °C
Storage Comment Upon receipt aliquot and store at -20 C
Supplier Images
Western Blotting (WB) image for anti-Nucleoporin 153kDa (NUP153) (AA 610-1191) antibody (ABIN2452062) anti-Nucleoporin 153kDa (NUP153) (AA 610-1191) antibody
Immunofluorescence (IF) image for anti-Nucleoporin 153kDa (NUP153) (AA 610-1191) antibody (ABIN2452062) anti-Nucleoporin 153kDa (NUP153) (AA 610-1191) antibody (Image 2)
Immunofluorescence (IF) image for anti-Nucleoporin 153kDa (NUP153) (AA 610-1191) antibody (ABIN2452062) anti-Nucleoporin 153kDa (NUP153) (AA 610-1191) antibody (Image 3)
Product cited in: Lim, Fahrenkrog, Köser, Schwarz-Herion, Deng, Aebi: "Nanomechanical basis of selective gating by the nuclear pore complex." in: Science (New York, N.Y.), Vol. 318, Issue 5850, pp. 640-3, 2007 (PubMed).

Ullman, Shah, Powers, Forbes: "The nucleoporin nup153 plays a critical role in multiple types of nuclear export." in: Molecular biology of the cell, Vol. 10, Issue 3, pp. 649-64, 1999 (PubMed).

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