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PHLDA3 antibody (N-Term)

PHLDA3 Reactivity: Human WB Host: Mouse Monoclonal 4B6 unconjugated
Catalog No. ABIN2452076
  • Target See all PHLDA3 Antibodies
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Binding Specificity
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-31, N-Term
    Reactivity
    • 21
    • 7
    • 7
    • 2
    • 2
    • 1
    Human
    Host
    • 19
    • 1
    • 1
    Mouse
    Clonality
    • 20
    • 1
    Monoclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHLDA3 antibody is un-conjugated
    Application
    • 11
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Specific to human PHLDA3.
    Cross-Reactivity (Details)
    Not tested in other species.
    Characteristics
    The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.
    Purification
    Purified
    Sterility
    Sterile filtered
    Immunogen
    Synthetic peptide corresponding to N terminal aa 1-31 of human PHLDA3
    Clone
    4B6
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product PHLDA3 Primary Antibody
  • Application Notes
    Other applications were not tested.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol
    Preservative
    Azide free
    Storage
    -20 °C/-80 °C
    Storage Comment
    -20 C (For long term storage: -70 C)
  • Kawase, Ohki, Shibata, Tsutsumi, Kamimura, Inazawa, Ohta, Ichikawa, Aburatani, Tashiro, Taya: "PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt." in: Cell, Vol. 136, Issue 3, pp. 535-50, (2009) (PubMed).

  • Target
    PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))
    Alternative Name
    PHLDA3 (PHLDA3 Products)
    Synonyms
    TIH1 antibody, Tih1 antibody, si:dz182n13.5 antibody, zgc:92333 antibody, pleckstrin homology like domain family A member 3 antibody, pleckstrin homology like domain, family A, member 3 antibody, pleckstrin homology-like domain, family A, member 3 antibody, PHLDA3 antibody, Phlda3 antibody, phlda3 antibody
    Background
    PHLDA3 (Pleckstrin homology-like domain family A member 3) is a small PH (Pleckstrin homology) domain-only protein (127 a.a. in human) that is highly conserved in vertebrates. Recently PHLDA3 was found to be a p53-regulated repressor of Akt hence it is speculated as a tumor suppressor. PHLDA3 also inhibits anchorage-independent cell growth. PHLDA3 gene is frequently lost in human lung endocrine tumors.
    UniProt
    Q9Y5J5
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