PANK2 antibody

Catalog No. ABIN2728202

Product Details anti-PANK2 Antibody

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Reactivity: Human, Rat, Dog, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PANK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PANK2(NP_705902) produced in HEK293T cell.

Clone: 3H9

Isotype: IgG2a

Application Details

Application Notes: WB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-PANK2 antibody (ABIN2728202)

Santambrogio, Dusi, Guaraldo, Rotundo, Broccoli, Garavaglia, Tiranti, Levi: "Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients." in: Neurobiology of disease, (2015) (PubMed).

Huang, Chu, Jiang, Chen, Zhang, Zeng: "Glycyrrhizin suppresses lung adenocarcinoma cell growth through inhibition of thromboxane synthase." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 33, Issue 2, pp. 375-88, (2014) (PubMed).

Zeman, Lin, Freire, Cimprich: "DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis." in: The Journal of cell biology, Vol. 206, Issue 2, pp. 183-97, (2014) (PubMed).

Barrett, Fang, Gargano, Markovich, Kocarek, Runge-Morris: "Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 41, Issue 8, pp. 1505-13, (2013) (PubMed).

Brunetti, Dusi, Morbin, Uggetti, Moda, DAmato, Giordano, dAmati, Cozzi, Levi, Hayflick, Tiranti: "Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model." in: Human molecular genetics, Vol. 21, Issue 24, pp. 5294-305, (2012) (PubMed).

Target Details for PANK2

Target: PANK2 (Pantothenate Kinase 2 (PANK2))

Alternative Name: PANK2 (PANK2 Products)

Synonyms: ATPANK2 antibody, F10M6.180 antibody, F10M6_180 antibody, pantothenate kinase 2 antibody, PANK2 antibody, C20orf48 antibody, HARP antibody, HSS antibody, NBIA1 antibody, PKAN antibody, 4933409I19Rik antibody, AI642621 antibody, pantothenate kinase 2 antibody, pantothenate kinase 2, mitochondrial antibody, ribonuclease A family member 11 (inactive) antibody, PANK2 antibody, Tsp_01576 antibody, LOC100539295 antibody, Pank2 antibody, RNASE11 antibody

Molecular Weight: 59.1 kDa

Gene ID: 80025

NCBI Accession: NM_153638

HGNC: 80025

Pathways: Ribonucleoside Biosynthetic Process