RNF144B antibody (AA 1-256)

Catalog No. ABIN2731030

Product Details anti-RNF144B Antibody

Target: RNF144B (Ring Finger Protein 144B (RNF144B))

Binding Specificity: AA 1-256

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RNF144B antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Homo sapiens ring finger protein 144B (RNF144B)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 1-256 of human RNF144B (NP_877434) produced in E. coli.

Clone: 10A12

Isotype: IgG1

Application Details

Application Notes: WB 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RNF144B

Target: RNF144B (Ring Finger Protein 144B (RNF144B))

Alternative Name: RNF144B (RNF144B Products)

Synonyms: IBRDC2 antibody, PIR2 antibody, bA528A10.3 antibody, p53RFP antibody, BC025007 antibody, E130105P19Rik antibody, Ibrdc2 antibody, Pir2 antibody, ring finger protein 144B antibody, RNF144B antibody, Rnf144b antibody

Background: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, thereby promoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism.

Molecular Weight: 33.7 kDa

Gene ID: 255488

NCBI Accession: NM_182757

HGNC: 255488