PTPRE antibody

Catalog No. ABIN2730136

Product Details anti-PTPRE Antibody

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPRE antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Homo sapiens protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.

Clone: 3B8

Isotype: IgG1

Application Details

Application Notes: WB 1:500, IF 1:100, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PTPRE

Target: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Alternative Name: PTPRE (PTPRE Products)

Synonyms: ptpra antibody, HPTPE antibody, PTPE antibody, R-PTP-EPSILON antibody, PTPe antibody, PTPepsilon antibody, RPTPepsilon antibody, protein tyrosine phosphatase, receptor type E L homeolog antibody, protein tyrosine phosphatase, receptor type E antibody, protein tyrosine phosphatase, receptor type, E antibody, ptpre.L antibody, PTPRE antibody, Ptpre antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region,and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Molecular Weight: 80.6 kDa

Gene ID: 5791

NCBI Accession: NM_006504

HGNC: 5791