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SAMHD1 antibody

SAMHD1 Reactivity: Human WB, IF, FACS Host: Mouse Monoclonal 2D7 unconjugated
Catalog No. ABIN2731369
  • Target See all SAMHD1 Antibodies
    SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
    Reactivity
    • 49
    • 30
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 69
    • 4
    Mouse
    Clonality
    • 61
    • 12
    Monoclonal
    Conjugate
    • 30
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SAMHD1 antibody is un-conjugated
    Application
    • 50
    • 23
    • 15
    • 14
    • 9
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Characteristics
    Homo sapiens SAM domain and HD domain 1 (SAMHD1)
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.
    Clone
    2D7
    Isotype
    IgG2b
    Top Product
    Discover our top product SAMHD1 Primary Antibody
  • Application Notes
    WB 1:2000, IF 1:100, FLOW 1:100
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Jeong, Park, Ahn, Ahn: "Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." in: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).

    Hertoghs, van der Aar, Setiawan, Kootstra, Gringhuis, Geijtenbeek: "SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4431-7, (2015) (PubMed).

    Pan, Pan, Weng, Zhao, Zhang, Wang, Lv, Jiang, Zheng, Xia: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).

    Zhang, Bloch, Nguyen, Kim, Landau: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).

  • Target
    SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
    Alternative Name
    SAMHD1 (SAMHD1 Products)
    Synonyms
    CHBL2 antibody, DCIP antibody, HDDC1 antibody, MOP-5 antibody, SBBI88 antibody, si:dkeyp-44b8.8 antibody, E330031J07Rik antibody, Mg11 antibody, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 antibody, SAM domain and HD domain 1 antibody, SAM domain and HD domain, 1 antibody, SAMHD1 antibody, samhd1 antibody, Samhd1 antibody
    Background
    This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. COMPLETENESS: complete on the 3' end.
    Molecular Weight
    72 kDa
    Gene ID
    25939
    NCBI Accession
    NM_015474
    HGNC
    25939
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