RNH1 antibody

Catalog No. ABIN2730893

Product Details anti-RNH1 Antibody

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RNH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Homo sapiens ribonuclease/angiogenin inhibitor 1 (RNH1), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human RNH1(NP_002930) produced in HEK293T cell.

Clone: 2B1

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RNH1

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Alternative Name: RNH1 (RNH1 Products)

Synonyms: RAI antibody, RNH antibody, AW546468 antibody, C80305 antibody, RNH1 antibody, Rnh antibody, Rnh1 antibody, im:7039360 antibody, si:ch211-213a13.3 antibody, wu:fd55g05 antibody, ribonuclease/angiogenin inhibitor 1 antibody, ribonuclease inhibitor antibody, RNH1 antibody, Rnh1 antibody, Tc00.1047053511893.10 antibody, Tc00.1047053507583.70 antibody, rnh1 antibody

Background: Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

Molecular Weight: 49.8 kDa

Gene ID: 6050

NCBI Accession: NM_002939

HGNC: 6050