Annexin A3 antibody

Catalog No. ABIN2716166

Product Details anti-Annexin A3 Antibody

Target: Annexin A3 (ANXA3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Homo sapiens annexin A3 (ANXA3)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ANXA3 (NP_005130) produced in HEK293T cell.

Clone: 1F11

Isotype: IgG2b

Application Details

Application Notes: WB 1:500~2000, IHC 1:150,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-Annexin A3 antibody (ABIN2716166)

Wang, Li: "Overexpression of ANXA3 is an independent prognostic indicator in gastric cancer and its depletion suppresses cell proliferation and tumor growth." in: Oncotarget, Vol. 7, Issue 52, pp. 86972-86984, (2018) (PubMed).

Pan, Pan, Weng, Zhao, Zhang, Wang, Lv, Jiang, Zheng, Xia: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).

Pan, Pan, Wang, Weng, Zhao, Zheng, Zhang, Jiang, Lv, Tang, Li, He, Liu, Chen, Zhang, Xia: "Annexin A3 as a potential target for immunotherapy of liver cancer stem-like cells." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 2, pp. 354-66, (2015) (PubMed).

Mercado, Kizawa, Ueda, Xiong, Kimura, Moses, Curtis, Ito, Barnes: "Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers." in: PLoS ONE, Vol. 9, Issue 2, pp. e88168, (2014) (PubMed).

Target Details for Annexin A3

Target: Annexin A3 (ANXA3)

Alternative Name: ANXA3 (ANXA3 Products)

Synonyms: MGC80326 antibody, anxa3 antibody, zgc:101718 antibody, ANXA3 antibody, ANX3 antibody, Anx3 antibody, LC3 antibody, LRRGT00047 antibody, annexin A3 L homeolog antibody, annexin A3a antibody, annexin A3 antibody, Annexin A3 antibody, anxa3.L antibody, anxa3a antibody, ANXA3 antibody, anxa3 antibody, Anxa3 antibody

Background: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Molecular Weight: 36.2 kDa

Gene ID: 306

NCBI Accession: NM_005139

HGNC: 306