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CTNNB1 antibody

CTNNB1 Reactivity: Human, Rat, Dog, Monkey WB, IHC, FACS Host: Mouse Monoclonal 9H2 unconjugated
Catalog No. ABIN2717125
  • Target See all CTNNB1 Antibodies
    CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
    Reactivity
    • 229
    • 128
    • 113
    • 33
    • 24
    • 24
    • 19
    • 17
    • 12
    • 11
    • 11
    • 9
    • 8
    • 7
    • 6
    • 5
    • 1
    Human, Rat, Dog, Monkey
    Host
    • 154
    • 74
    • 3
    • 2
    Mouse
    Clonality
    • 150
    • 83
    Monoclonal
    Conjugate
    • 197
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTNNB1 antibody is un-conjugated
    Application
    • 205
    • 96
    • 95
    • 77
    • 52
    • 48
    • 34
    • 33
    • 13
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Characteristics
    Homo sapiens catenin (cadherin-associated protein), beta 1, 88 kDa (CTNNB1), transcript variant 1
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Full length human recombinant protein of human CTNNB1 (NP_001895) produced in HEK293T cell.
    Clone
    9H2
    Isotype
    IgG2b
    Top Product
    Discover our top product CTNNB1 Primary Antibody
  • Application Notes
    WB 1:1000~2000, IHC 1:150, FLOW 1:100
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
    Alternative Name
    CTNNB1 (CTNNB1 Products)
    Synonyms
    Jup antibody, LOC100217813 antibody, CTNNB1 antibody, CTNNB antibody, Bfc antibody, Catnb antibody, Mesc antibody, ctnnb antibody, id:ibd2058 antibody, wu:fb73e10 antibody, wu:fi81c06 antibody, wu:fk25h01 antibody, ctnnb1 antibody, CHBCAT antibody, MRD19 antibody, armadillo antibody, beta-catenin antibody, catenin beta 1 antibody, catenin (cadherin associated protein), beta 1 antibody, catenin (cadherin-associated protein), beta 1 antibody, catenin beta 1 S homeolog antibody, catenin beta 1 L homeolog antibody, CTNNB1 antibody, Ctnnb1 antibody, ctnnb1 antibody, ctnnb1.S antibody, ctnnb1.L antibody
    Background
    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
    Molecular Weight
    85.3 kDa
    Gene ID
    1499
    NCBI Accession
    NM_001904
    HGNC
    1499
    Pathways
    WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
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