BAIAP2 antibody

Catalog No. ABIN2716512

Product Details anti-BAIAP2 Antibody

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAIAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Homo sapiens BAI1-associated protein 2 (BAIAP2), transcript variant 3

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human BAIAP2(NP_005331) produced in HEK293 cell.

Clone: 1C10

Isotype: IgG2a

Application Details

Application Notes: WB 1:2000, IF 1:100, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Alternative Name: BAIAP2 (BAIAP2 Products)

Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 57.3 kDa

Gene ID: 10458

NCBI Accession: NM_006340

HGNC: 10458