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SIRT6 antibody (AA 88-352)

SIRT6 Reactivity: Human WB, IF Host: Mouse Monoclonal 1G3 unconjugated
Catalog No. ABIN2732083
  • Target See all SIRT6 Antibodies
    SIRT6 (Sirtuin 6 (SIRT6))
    Binding Specificity
    • 16
    • 15
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 88-352
    Reactivity
    • 92
    • 31
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 88
    • 12
    • 2
    Mouse
    Clonality
    • 83
    • 19
    Monoclonal
    Conjugate
    • 53
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRT6 antibody is un-conjugated
    Application
    • 83
    • 40
    • 36
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Characteristics
    Homo sapiens sirtuin 6 (SIRT6), transcript variant 1
    Purification
    Purified from mouse ascites fluids by affinity chromatography
    Immunogen
    Human recombinant protein fragment corresponding to amino acids 88-352 of human SIRT6(NP_057623) produced in E.coli.
    Clone
    1G3
    Isotype
    IgG1
    Top Product
    Discover our top product SIRT6 Primary Antibody
  • Application Notes
    WB 1:500~2000, IF 1:100,
    Comment

    The concentration of the product may vary between diferrent lots.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5-1.0 mg/mL
    Buffer
    PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Sugatani, Agapova, Malluche, Hruska: "SIRT6 deficiency culminates in low-turnover osteopenia." in: Bone, Vol. 81, pp. 168-77, (2015) (PubMed).

  • Target
    SIRT6 (Sirtuin 6 (SIRT6))
    Alternative Name
    SIRT6 (SIRT6 Products)
    Synonyms
    2810449N18Rik antibody, AI043036 antibody, Sir2l6 antibody, SIR2L6 antibody, zgc:86729 antibody, sirtuin 6 antibody, sirtuin 6 S homeolog antibody, Sirt6 antibody, SIRT6 antibody, sirt6.S antibody, sirt6 antibody
    Background
    This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
    Molecular Weight
    38.9 kDa
    Gene ID
    51548
    NCBI Accession
    NM_016539
    HGNC
    51548
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