PTPN7 antibody

Catalog No. ABIN2730123

Product Details anti-PTPN7 Antibody

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Reactivity: Human, Mouse, Rat, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTPN7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Characteristics: Homo sapiens protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human PTPN7(NP_542155) produced in HEK293T cell.

Clone: 3B10

Isotype: IgG2b

Application Details

Application Notes: WB 1:500~2000, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for PTPN7

Target: PTPN7 (Protein tyrosine Phosphatase, Non-Receptor Type 7 (PTPN7))

Alternative Name: PTPN7 (PTPN7 Products)

Synonyms: BPTP-4 antibody, HEPTP antibody, LC-PTP antibody, LPTP antibody, PTPNI antibody, C920001D21Rik antibody, Heptp antibody, Lcptp antibody, protein tyrosine phosphatase, non-receptor type 7 antibody, PTPN7 antibody, Ptpn7 antibody

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 44.8 kDa

Gene ID: 5778

NCBI Accession: NM_080588

HGNC: 5778