EIF2B3 antibody

Catalog No. ABIN2720067

Product Details anti-EIF2B3 Antibody

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Reactivity: Human, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This EIF2B3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Homo sapiens eukaryotic translation initiation factor 2B, subunit 3 gamma, 58 kDa (EIF2B3), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human EIF2B3(NP_065098) produced in HEK293T cell.

Clone: 1A4

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, IHC 1:150, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for EIF2B3

Target: EIF2B3 (Eukaryotic Translation Initiation Factor 2B, Subunit 3 Gamma, 58kDa (EIF2B3))

Alternative Name: EIF2B3 (EIF2B3 Products)

Synonyms: zgc:56473 antibody, 1190002P15Rik antibody, EIF-2B antibody, EIF2Bgamma antibody, eukaryotic translation initiation factor 2B subunit gamma L homeolog antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma antibody, eukaryotic translation initiation factor 2B subunit gamma antibody, eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa antibody, eukaryotic translation initiation factor 2B, subunit 3 antibody, eif2b3.L antibody, eif2b3 antibody, EIF2B3 antibody, Eif2b3 antibody

Background: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 50.1 kDa

Gene ID: 8891

NCBI Accession: NM_020365

HGNC: 8891