RBBP7 antibody

Catalog No. ABIN2730582

Product Details anti-RBBP7 Antibody

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RBBP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Characteristics: Homo sapiens retinoblastoma binding protein 7 (RBBP7), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human RBBP7(NP_002884) produced in HEK293T cell.

Clone: 2D8

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RBBP7

Target: RBBP7 (Retinoblastoma Binding Protein 7 (RBBP7))

Alternative Name: RBBP7 (RBBP7 Products)

Synonyms: RbAp46 antibody, AA409861 antibody, AI173248 antibody, AU019541 antibody, BB114024 antibody, mRbAp46 antibody, rbap46 antibody, RBBP7 antibody, RBBP-7 antibody, Caf1 antibody, rbbp7 antibody, wu:fa13g08 antibody, wu:fb50h10 antibody, wu:fc29d09 antibody, zgc:56477 antibody, zgc:85617 antibody, CaO19.2146 antibody, RB binding protein 7, chromatin remodeling factor antibody, retinoblastoma binding protein 7, chromatin remodeling factor antibody, retinoblastoma binding protein 7 L homeolog antibody, retinoblastoma binding protein 7 antibody, retinoblastoma binding protein 4, like antibody, histone-binding protein RBBP7 antibody, Hat2p antibody, RBBP7 antibody, Rbbp7 antibody, rbbp7.L antibody, rbbp7 antibody, rbb4l antibody, LOC108708306 antibody, HAT2 antibody

Background: This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 47.6 kDa

Gene ID: 5931

NCBI Accession: NM_002893

HGNC: 5931