TIMP2 antibody

Catalog No. ABIN2733753

Product Details anti-TIMP2 Antibody

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Characteristics: Homo sapiens TIMP metallopeptidase inhibitor 2 (TIMP2)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human TIMP2(NP_003246) produced in HEK293T cell.

Clone: 1B11

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: TIMP2 (TIMP2 Products)

Synonyms: CSC-21K antibody, DDC8 antibody, timp2l antibody, zgc:65967 antibody, zgc:85799 antibody, D11Bwg1104e antibody, Timp-2 antibody, TIMP-2 antibody, etID32613.12 antibody, fa96h09 antibody, timp2 antibody, wu:fa96h09 antibody, zgc:136726 antibody, TIMP metallopeptidase inhibitor 2 antibody, TIMP metallopeptidase inhibitor 2b antibody, tissue inhibitor of metalloproteinase 2 antibody, TIMP metallopeptidase inhibitor 2a antibody, TIMP metallopeptidase inhibitor 2 L homeolog antibody, TIMP2 antibody, timp2b antibody, Timp2 antibody, timp2a antibody, timp2.L antibody

Background: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

Molecular Weight: 21.7 kDa

Gene ID: 7077

NCBI Accession: NM_003255

HGNC: 7077

Pathways: cAMP Metabolic Process