SERPINB6 antibody

Catalog No. ABIN2731814

Product Details anti-SERPINB6 Antibody

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SERPINB6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 6 (SERPINB6), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human SERPINB6(NP_004559) produced in HEK293T cell.

Clone: 2F8

Isotype: IgG2a

Application Details

Application Notes: WB 1:500~2000, IHC 1:150,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for SERPINB6

Target: SERPINB6 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 6 (SERPINB6))

Alternative Name: SERPINB6 (SERPINB6 Products)

Synonyms: Serpinb6a antibody, cap antibody, dfnb91 antibody, mstp057 antibody, pi6 antibody, pti antibody, serpinb8 antibody, spi3 antibody, 4930482L21Rik antibody, D330015H01Rik antibody, PI-6 antibody, Serpinb6 antibody, Spi3 antibody, ovalbumin antibody, CAP antibody, DFNB91 antibody, MSTP057 antibody, PI6 antibody, PTI antibody, SPI3 antibody, serpin family B member 6A antibody, serpin family B member 6 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 6a antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 6 antibody, Serpinb6a antibody, serpinb6 antibody, SERPINB6 antibody

Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene.

Gene ID: 5269

NCBI Accession: NM_004568

HGNC: 5269