Frataxin antibody

Catalog No. ABIN2721402

Product Details anti-Frataxin Antibody

Target: Frataxin (FXN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Frataxin antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Homo sapiens frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human FXN(NP_000135) produced in HEK293T cell.

Clone: 3C7

Isotype: IgG1

Application Details

Application Notes: WB 1:1000,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Frataxin

Target: Frataxin (FXN)

Alternative Name: FXN (FXN Products)

Synonyms: zgc:158218 antibody, LOC100284365 antibody, BcDNA:AT09528 antibody, CG8971 antibody, DFH antibody, Dfh antibody, Dmel\\CG8971 antibody, X25 antibody, dfh antibody, CyaY antibody, FA antibody, FARR antibody, FRDA antibody, RGD1565754 antibody, Frda antibody, frataxin antibody, fxn antibody, LOC100284365 antibody, TVAG_182150 antibody, fh antibody, FTX1 antibody, FXN antibody, Fxn antibody

Background: This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

Molecular Weight: 18.8 kDa

Gene ID: 2395

NCBI Accession: NM_000144

HGNC: 2395

Pathways: Transition Metal Ion Homeostasis, Regulation of Cell Size